SIRT5 antibody

Catalogue Number: GTX85104-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:34
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:sirtuin 5 , SIR2L5
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: SIRT5 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human SIRT5.The immunogen is located within the last 50 amino acids of SIRT5.
Application: ELISA, WB

Description

Description: The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence and lifespan extension. Sirtuins, including SIRT1-7, are human homologs of yeast Sir2p. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) which regulate cellular metabolism, e.g. energy metabolism, and thereby are associated with aging and several age-related diseases. SIRT5 localizes to mitochondria, deacetylates carbamoyl phosphate synthetase 1, and is involved in the regulation of the urea cycle.

Additional Text

Gene Name

SIRT5

Uniprot ID

Q9NXA8

Gene ID

23408

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

34

Concentration

1 mg/ml

Application Notes

WB: 1 - 2 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.