AP2M1 antibody
Catalogue Number: GTX85110-GTX
GTX85110 Image
GTX85110 Image
GTX85110 Image
GTX85110 Image
IHC-P analysis of mouse kidney tissue using GTX85110 AP2M1 antibody. Working concentration : 2.5 µg/ml
GTX85110 Image
WB analysis of human kidney tissue lysate using GTX85110 AP2M1 antibody. Working concentration : (A) 1 and (B) 2 µg/ml
GTX85110 Image
IHC-P analysis of mouse kidney tissue using GTX85110 AP2M1 antibody. Working concentration : 20 µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 50 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | adaptor related protein complex 2 subunit mu 1 , AP50 , CLAPM1 , mu2 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | AP2M1 antibody was raised against a 16 amino acid synthetic peptide near the carboxy terminus of human AP2M1.The immunogen is located within amino acids 360 - 410 of AP2M1. |
| Application: | ELISA, IHC-P, WB |
Description
Description: The heterotetrameric coat assembly protein complex, also known as the adaptor-related protein complex 2 (AP-2), belongs to the adaptor complexes medium subunits family. The mu 1 subunit of the AP-2 complex (AP2M1) is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. AP2M1 has also been shown to associate with the HIV-1 protein Nef, suggesting that Nef may use AP-2 complex to enhance the rate of endocytosis of both CD4 and class I MHC. AP2M1 may also play an important role in regulating the intracellular trafficking and function of cytotoxic T-lymphocyte associated (CTLA)-4 protein. At least two isoforms of AP2M1 are known to exist.
Additional Text
Gene Name
AP2M1
Gene ID
1173
Uniprot ID
Q96CW1
Purification
Affinity Purified
Molecular Weight
50
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Concentration
1 mg/ml
Application Notes
WB: 1 - 2 µg/mL. IHC-P: 2.5 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX85110 Datasheet
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