Prealbumin antibody

Catalogue Number: GTX85112-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:16
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:transthyretin , ATTR , CTS , CTS1 , HEL111 , HsT2651 , PALB , TBPA
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Chicken
Clone:
Isotype: IgY
Immunogen: Transthyretin antibody was raised against a 17 amino acid synthetic peptide near the center of human Transthyretin.The immunogen is located within amino acids 40 - 90 of Transthyretin.
Application: ELISA, IHC-P, WB

Description

Description: Transthyretin is a tetrameric carrier protein that transports thyroid hormones in the plasma and cerebrospinal fluid, and retinol (vitamin A) in the plasma. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart. The diseases caused by mutations include familial amyloidotic polyneuropathy, euthyroid hyperthyroxinemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, and carpal tunnel syndrome. It has also been suggested that Transthyretin plays an important role in the maintenance of normal cognitive processes during aging, neuropeptide processing and nerve regeneration. It has also been linked to several pathological conditions including Parkinson's disease, schizophrenia, and depression.

Additional Text

Gene Name

TTR

Uniprot ID

P02766

Gene ID

7276

Purification

Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

16

Concentration

1 mg/ml

Application Notes

WB: 1 - 2 µg/mL. IHC-P: 2.5 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.