Myelin basic protein antibody
Catalogue Number: GTX85456-GTX
GTX85456 Image
GTX85456 Image
GTX85456 Image
GTX85456 Image
IHC analysis of hippocampal region of a transgenic adult mouse brain using GTX85456 Myelin basic protein antibody. This particular transgenic mouse expresses low levels of GFP autofluorescence until control of an actin promoter region. Red : Primary antibody Dilution : 1:1000
GTX85456 Image
IHC analysis of sciatic nerve of an adult rat using GTX85456 Myelin basic protein antibody. Green : Primary antibody Red : ubliquitous gene product Blue : DAPI
GTX85456 Image
IHC analysis of sciatic nerve of an adult rat using GTX85456 Myelin basic protein antibody. Green : Primary antibody Red : ubliquitous gene product Blue : DAPI
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 33 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Myelin basic protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug |
| Host name: | Chicken |
| Clone: | |
| Isotype: | IgY |
| Immunogen: | Chickens were immunized with a synthetic peptide / keyhole limpet hemocyanin (KLH) conjugate. The peptide corresponded to a region of the MBP gene product shared between the human (NP_002376, NCBI) and mouse (NP_034907, NCBI) sequences. |
| Application: | ICC, IF, WB, IHC |
Description
Description: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called "Golli-MBP") that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
MBP
Gene ID
4155
Concentration
100 ug/ml
Purification
Affinity Purified
Uniprot ID
P02686
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
33
Application Notes
WB: 1:1000-1:2000. IHC: 1:1000-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE.
GTX85456 Datasheet
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