PTPRB antibody, Internal
Catalogue Number: GTX88020-GTX
GTX88020 Image
GTX88020 Image
GTX88020 Image
FACS analysis of PFA-fixed A431 cells using GTX88020 PTPRB antibody, Internal. Blue : Primary antibody Black : Unimmunized goat IgG Permeabilization : 0.5% Triton Dilution : 10ug/ml
GTX88020 Image
ICC/IF analysis of PFA-fixed A431 cells using GTX88020 PTPRB antibody, Internal. Negative control (-ve) : Unimmunized goat IgG Permeabilization : 0.15% Triton Dilution : 10ug/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | protein tyrosine phosphatase receptor type B , HPTP-BETA , HPTPB , PTPB , R-PTP-BETA , VEPTP |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence C-ENHSFSQERTVPDK, from the internal region of the protein sequence according to NP_001103224.1; NP_002828.3. |
| Application: | FC, ICC, IF |
Description
Description: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Additional Text
Concentration
0.5 mg/ml
Gene Name
PTPRB
Uniprot ID
P23467
Gene ID
5787
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX88020 Datasheet
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