AMPK alpha 2 antibody, Internal
Catalogue Number: GTX88046-GTX
GTX88046 Image
GTX88046 Image
GTX88046 Image
GTX88046 Image
ELISA analysis of AMPK alpha 2 protein using GTX88046 AMPK alpha 2 antibody, Internal. Capture : GTX113251 (2.5µg/ml) Detection : GTX88046 (1.5µg/ml)
GTX88046 Image
WB analysis of mouse (A) and rat (B) heart lysate using GTX88046 AMPK alpha 2 antibody, Internal. Dilution : 0.3µg/ml Loading : 35µg protein in RIPA buffer
GTX88046 Image
WB analysis of human liver lysate using GTX88046 AMPK alpha 2 antibody, Internal. Dilution : 1µg/ml Loading : 35µg protein in RIPA buffer
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 62 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | protein kinase AMP-activated catalytic subunit alpha 2 , AMPK , AMPK2 , AMPKa2 , PRKAA |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence CPLDALNTTKP, from the internal region of the protein sequence according to NP_006243.2. |
| Application: | ELISA, sELISA, WB |
Description
Description: The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
PRKAA2
Uniprot ID
P54646
Concentration
0.5 mg/ml
Gene ID
5563
Molecular Weight
62
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Application Notes
WB: 0.3-1µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX88046 Datasheet
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