PGC1 alpha antibody, Internal
Catalogue Number: GTX89046-GTX
GTX89046 Image
GTX89046 Image
GTX89046 Image
GTX89046 Image
GTX89046 Image
GTX89046 Image
The data was published in the journal BMC Complement Altern Med in 2019. PMID: 31488120
GTX89046 Image
FACS analysis of PFA-fixed HeLa cells using GTX89046 PGC1 alpha antibody, Internal. Blue line : Primary antibody Black line : Isotype control Permeabilization : 0.5% Triton Dilution : 10 µg/mL
GTX89046 Image
ICC/IF analysis of PFA-fixed HeLa cells using GTX89046 PGC1 alpha antibody, Internal. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10 µg/mL
GTX89046 Image
ICC/IF analysis of PFA-fixed U2OS cells using GTX89046 PGC1 alpha antibody, Internal. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton X-100 Dilution : 10 µg/mL
GTX89046 Image
IHC-P analysis of human kidney tissue using GTX89046 PGC1 alpha antibody, Internal. Antigen retrieval: Heat mediated antigen retrieval in citrate buffer (pH 6). Dilution : 6 µg/mL
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 91 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | PPARG coactivator 1 alpha , LEM6 , PGC-1(alpha) , PGC-1alpha , PGC-1v , PGC1 , PGC1A , PPARGC1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence C-DGLFDDSEDESDK, from the internal region of the protein sequence according to NP_037393.1. |
| Application: | FC, ICC, IF, IHC-P, WB |
Description
Description: The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity. [provided by RefSeq, Jul 2008]
Additional Text
Uniprot ID
Q9UBK2
Concentration
0.5 mg/ml
Gene Name
PPARGC1A
Gene ID
10891
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
91
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.3-1 µg/mL. ICC/IF: 10 µg/mL. IHC-P: 6-8 µg/mL. FCM: 10 µg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX89046 Datasheet
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