SBP2 antibody, Internal

Catalogue Number: GTX89253-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	95
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	SECIS binding protein 2 , SBP2
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Goat
Clone:
Isotype:	IgG
Immunogen:	Peptide with sequence C-KERQERKQRLQEN, from the internal region of the protein sequence according to NP_076982.3.
Application:	ICC, IF, IHC-P, IP, WB

Overview
Datasheets

Description

Description: The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]

Additional Text

Gene Name

SECISBP2

Concentration

0.5 mg/ml

Uniprot ID

Q96T21

Gene ID

79048

Molecular Weight

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 0.1-0.3µg/ml. IHC-P: 3µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX89253 Datasheet

Price

£410.00

-

Quantity
Unit Size

Find out about delivery