COMT antibody, Internal
Catalogue Number: GTX89277-GTX
GTX89277 Image
GTX89277 Image
GTX89277 Image
GTX89277 Image
GTX89277 Image
GTX89277 Image
WB analysis of human testis lysate using GTX89277 COMT antibody, Internal. Dilution : 0.3µg/ml Loading : 35µg protein in RIPA buffer
GTX89277 Image
ELISA analysis of COMT protein using GTX89277 COMT antibody, Internal. Capture : GTX101233 (2.5µg/ml) Detection : GTX89277 (0.5µg/ml)
GTX89277 Image
IHC-P analysis of human small intestine using GTX89277 COMT antibody, Internal. Antigen retrieval : citrate buffer pH 6 Dilution : 3.75µg/ml
GTX89277 Image
IHC-P analysis of human testis using GTX89277 COMT antibody, Internal. Antigen retrieval : citrate buffer pH 6 Dilution : 3.75µg/ml
GTX89277 Image
IHC-P analysis of human cerebellum using GTX89277 COMT antibody, Internal. Antigen retrieval : Tris/EDTA buffer pH 9 Dilution : 4µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 30 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | catechol-O-methyltransferase , HEL-S-98n |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence C-QDIIPQLKKKYDVD, from the internal region of the protein sequence according to NP_000745.1; NP_009294.1. |
| Application: | ELISA, IHC-P, sELISA, WB |
Description
Description: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
Additional Text
Gene Name
COMT
Uniprot ID
P21964
Gene ID
1312
Concentration
0.5 mg/ml
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
30
Application Notes
WB: 0.03-0.1µg/ml. IHC-P: 3.75µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
GTX89277 Datasheet
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