HP1 alpha antibody, Internal
Catalogue Number: GTX89432-GTX
GTX89432 Image
GTX89432 Image
GTX89432 Image
GTX89432 Image
WB analysis of K562 (A), MCF7 (B) and NIH-3T3 (C) cell lysate using GTX89432 HP1 alpha antibody, Internal. Dilution : 0.1µg/ml Loading : 35µg protein in RIPA buffer
GTX89432 Image
FACS analysis of PFA fixed HeLa cells using GTX89432 HP1 alpha antibody, Internal. Blue : Primary antibody Black : Isotype control Permeabilization : 0.5% Triton Dilution : 10µg/ml
GTX89432 Image
IHC-P analysis of human uterus using GTX89432 HP1 alpha antibody, Internal. Antigen retrieval : citrate buffer pH 6 Dilution : 2µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 22 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | chromobox 5 , HEL25 , HP1 , HP1A |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence C-NKRKSNFSNSADDIK, from the internal region of the protein sequence according to NP_036249.1; NP_001120793.1; NP_001120794.1. |
| Application: | FC, IHC-P, WB |
Description
Description: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
23468
Gene Name
CBX5
Uniprot ID
P45973
Concentration
0.5 mg/ml
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
22
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.03-0.1µg/ml. IHC-P: 2-4µg/ml. FCM: 10µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX89432 Datasheet
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