GDF15 antibody, C-term
Catalogue Number: GTX89503-GTX
GTX89503 Image
GTX89503 Image
GTX89503 Image
GTX89503 Image
GTX89503 Image
GTX89503 Image
WB analysis of human testes (A) and negative control skin (B) lysate using GTX89503 GDF15 antibody, C-term. Dilution : 0.3µg/ml Loading : 35µg protein in RIPA buffer
GTX89503 Image
WB analysis of HEK293 overexpressing GDF15 (mock transfection in first lane) using GTX89503 GDF15 antibody, C-term.
GTX89503 Image
FACS analysis of PFA fixed HeLa cells using GTX89503 GDF15 antibody, C-term. Blue : Primary antibody Black : Isotype control Permeabilization : 0.5% Triton Dilution : 10µg/ml
GTX89503 Image
IHC-P analysis of human placenta using GTX89503 GDF15 antibody, C-term. Antigen retrieval : citrate buffer pH 6 Dilution : 5µg/ml
GTX89503 Image
IHC-P analysis of human prostate using GTX89503 GDF15 antibody, C-term. Antigen retrieval : citrate buffer pH 6 Dilution : 5µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 34 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | growth differentiation factor 15 , GDF-15 , MIC-1 , MIC1 , NAG-1 , PDF , PLAB , PTGFB |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence C-QKTDTGVSLQTYDD, from the C Terminus of the protein sequence according to NP_004855.2. |
| Application: | FC, IHC-P, WB |
Description
Description: This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
Additional Text
Uniprot ID
Q99988
Gene ID
9518
Gene Name
GDF15
Concentration
0.5 mg/ml
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Molecular Weight
34
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.1-0.3µg/ml. IHC-P: 5µg/ml. FCM: 10µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX89503 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations