LRP5 antibody, Internal

Catalogue Number: GTX89521-GTX

Manufacturer:	GeneTex
Preservative:	0.02% Sodium azide\|0.02% Sodium azide
Molecular Weight:	179
Physical state:	Liquid
Type:	Polyclonal Primary Antibody - Unconjugated
Alias:	LDL receptor related protein 5 , BMND1 , EVR1 , EVR4 , HBM , LR3 , LRP-5 , LRP-7 , LRP7 , OPPG , OPS , OPTA1 , PCLD4 , VBCH2
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Goat
Clone:
Isotype:	IgG
Immunogen:	Peptide with sequence C-ERVEKTTGDKRT, from the internal region of the protein sequence according to NP_002326.2.
Application:	IHC-P, WB

Overview
Datasheets

Description

Description: This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Additional Text

Gene Name

LRP5

Uniprot ID

O75197

Concentration

0.5 mg/ml

Gene ID

4041

Molecular Weight

179

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1-3µg/ml. IHC-P: 2-4µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

GTX89521 Datasheet

Price

£410.00

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Quantity
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