MyD88 antibody, Internal

Catalogue Number: GTX89605-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:33
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:MYD88 innate immune signal transduction adaptor , MYD88D
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype: IgG
Immunogen: Peptide with sequence C-IKYKAMKKEFP, from the internal region of the protein sequence according to NP_001166038.1; NP_002459.2; NP_001166039.1.
Application: ELISA, IHC-P, sELISA, WB

Description

Description: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

Additional Text

Gene Name

MYD88

Gene ID

4615

Uniprot ID

Q99836

Concentration

0.5 mg/ml

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

33

Application Notes

WB: 0.1-0.3µg/ml. IHC-P: 4-6µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.