DKK1 antibody, C-term

Catalogue Number: GTX89683-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:29
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:dickkopf WNT signaling pathway inhibitor 1 , DKK-1 , SK
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype: IgG
Immunogen: Peptide with sequence CDHHQASNSSRLHT, from the C Terminus of the protein sequence according to NP_036374.1.
Application: FC, ICC, IF, IHC-P, WB

Description

Description: This gene encodes a member of the dickkopf family of proteins. Members of this family are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling. This gene plays a role in embryonic development and may be important in bone formation in adults. Elevated expression of this gene has been observed in numerous human cancers and this protein may promote proliferation, invasion and growth in cancer cell lines. [provided by RefSeq, Sep 2017]

Additional Text

Gene Name

DKK1

Gene ID

22943

Concentration

0.5 mg/ml

Uniprot ID

O94907

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Molecular Weight

29

Application Notes

WB: 1-3µg/ml. IHC-P: 10µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.