TRIM2 antibody, C-term

Catalogue Number: GTX89871-GTX

Manufacturer:GeneTex
Preservative:0.02% Sodium azide|0.02% Sodium azide
Molecular Weight:82
Physical state:Liquid
Type:Polyclonal Primary Antibody - Unconjugated
Alias:tripartite motif containing 2 , CMT2R , RNF86
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Goat
Clone:
Isotype: IgG
Immunogen: Peptide with sequence DSGNHCFKVYRYLQ, from the C Terminus of the protein sequence according to NP_056086.2; NP_001123539.1.
Application: ELISA, FC, IHC-P, WB

Description

Description: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Additional Text

Gene Name

TRIM2

Uniprot ID

Q9C040

Concentration

0.5 mg/ml

Gene ID

23321

Molecular Weight

82

Purification

Ammonium Sulfate Precipitated; Affinity Purified

Antibody Clonality

Polyclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Application Notes

WB: 0.5-2µg/ml. IHC-P: 6-12µg/ml. FCM: 10 µg/ml. ELISA: <1:16000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.