SOCS1 antibody, C-term
Catalogue Number: GTX89995-GTX
GTX89995 Image
GTX89995 Image
GTX89995 Image
GTX89995 Image
GTX89995 Image
GTX89995 Image
GTX89995 Image
WB analysis of human spleen (A), pig pancreas (B), (1ug/ml) mouse spleen (C) lysate and negative control HeLa (D) cell lysate using GTX89995 SOCS1 antibody, C-term. Dilution : 0.3µg/ml Loading : 35µg protein in RIPA buffer
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IHC-P analysis of human kidney using GTX89995 SOCS1 antibody, C-term. Antigen retrieval : citrate buffer pH 6 Dilution : 2.5µg/ml
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FACS analysis of PFA fixed HEK293 cells using GTX89995 SOCS1 antibody, C-term. Blue : Primary antibody Black : Isotype control Permeabilization : 0.5% Triton Dilution : 1µg/ml
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ICC/IF analysis of PFA fixed MCF7 cells using GTX89995 SOCS1 antibody, C-term. Green : Primary antibody Blue : DAPI Permeabilization : 0.15% Triton Dilution : 10µg/ml
GTX89995 Image
IHC-P analysis of paraffin embedded human kidney using GTX89995 SOCS1 antibody, C-term. Antigen retrieval : Heat induced antigen retrieval with citrate buffer pH 6 Dilution : 8µg/ml
GTX89995 Image
IHC-P analysis of paraffin embedded mouse kidney using GTX89995 SOCS1 antibody, C-term. Antigen retrieval : Heat induced antigen retrieval with citrate buffer pH 6 Dilution : 10µg/ml
| Manufacturer: | GeneTex |
| Preservative: | 0.02% Sodium azide|0.02% Sodium azide |
| Molecular Weight: | 24 |
| Physical state: | Liquid |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | suppressor of cytokine signaling 1 , CIS1 , CISH1 , JAB , SOCS-1 , SSI-1 , SSI1 , TIP-3 , TIP3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug |
| Host name: | Goat |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Peptide with sequence C-VLRDYLSSFPFQI, from the C Terminus of the protein sequence according to NP_003736.1. |
| Application: | FC, ICC, IF, IHC-P, WB |
Description
Description: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq, Jul 2008]
Additional Text
Gene Name
SOCS1
Uniprot ID
O15524
Gene ID
8651
Molecular Weight
24
Concentration
0.5 mg/ml
Purification
Ammonium Sulfate Precipitated; Affinity Purified
Antibody Clonality
Polyclonal
Note
For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4C. For long-term storage, aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Application Notes
WB: 0.1-1µg/ml. FCM: 10µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
GTX89995 Datasheet
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