Heparin, Heparan Sulfate (MaxLight 490)

Catalogue Number: H1892-22-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 2Q546
Isotype: IgG1
Immunogen:
Application: WB, RIA, FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Heparan Sulfate is a glycosaminoglycan, as is heparin. These proteoglycans bind proteins, including P-Selectin, and participate in the internalization of lipoproteins. It is thought that the protein- proteoglycan binding affinity comes from ionic interactions and the entropy generated by the release of cations upon protein binding.

Additional Text

Specificity

Recognizes heparin/heparan sulfate. Low affinity crossreactivity with DNA. Species Crossreactivity: mammals. It is reported that clone 2Q546 also cross reacts with dextran sulfate (Mahmood, 2002).

Purification

Purified

Antibody Clonality

Monoclonal