Hepatitis C Virus NS5a, aa2190-2300 (HCV) (MaxLight 650)
Catalogue Number: H1920-27D-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2B54 (7-D4) |
| Isotype: | IgG1 |
| Immunogen: | Recombinant protein corresponding to aa2190-2300 of HCV NS5a. |
| Application: | WB, IHC, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. Hepatitis C virus (HCV) represents the major etiologic agent of non-A, non-B hepatitis. The pathological changes in hepatitis C are characterized by the histologic triad of lymphoid aggregates in portal tracts, epithelial damage of small bile ducts, and micro-and macro-vesicular steatosis. HCV antigens are visible in the cytoplasm of infected hepatocytes by immunohistochemical staining with mono-or polyclonal antibodies. These studies are important to determine the viral load and expression pattern of HCV in the infected liver. The mechanism of hepatocyte and bile duct injury in HCV infection appears to be related to the host immune response to the virus. Direct viral cytopathogenicity may also play a role.
Additional Text
Specificity
Recognizes Hepatitis C Virus NS5a, aa2190-2300 (HCV).
Purification
Protein G purified
Antibody Clonality
Monoclonal
H1920-27D-ML650 Datasheet
SUPPORT
outstanding technical support
PRODUCT
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DELIVERY
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