HLA-DRA (HLA Class II Histocompatibility Antigen, DR alpha Chain, MHC Class II Antigen DRA, HLA-DRA1) (PerCP)

Catalogue Number: H6098-71E-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in 1ml saline, 0.5% BSA, 0.09% sodium azide. Labeled with Labeled with Peridinin-chlorophyll-protein complex (PerCP).
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	histocompatibility antigen HLA-DR alpha\|HLA class II histocompatibility antigen, DR alpha chain\|HLA-DRA1\|MHC class II antigen DRA
Shipping Condition:	Blue Ice
Unit(s):	100 Tests
Host name:	Mouse
Clone:	10K57
Isotype:	IgG1
Immunogen:	Recombinant human HLA-DR expressing RPMI8866 cells (Accession #P01903).
Application:	FC

Overview
Datasheets

Description

Description: HLA-DR is a transmembrane human major histocompatibility complex 2 (MHC II) family member, which consists of a 34kD (alpha) subunit and one of several 28kD (beta) subunits. HLA-DR is expressed primarily by B cells and dendritic cells (DC), where it binds peptides derived from internalized and processed antigenic proteins. It presents these peptides on the cell surface for recognition by the T cell receptor on CD4T cells. This interaction is central to antigen specificity in the adaptive immune response. HLA-DR alleles, polymorphisms, and aberrant expression are linked to a variety of diseases including autoimmunity and cancer.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

HLA-DRA

Gene ID

3122

Specificity

Recognizes human HLA-DR.

Purification

Protein G purified

Uniprot ID

P01903

Antibody Clonality

Monoclonal

H6098-71E Datasheet

Price

£857.00

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Quantity
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