HLA Class 2 Antigen DR (SLA Class II DR) (PE)

Catalogue Number: H6099-95Z-PE-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 10D419 (2E9/13)
Isotype: IgG2b
Immunogen: Porcine monocytes.
Application: FC, IP, IHC

Description

Description: Porcine SLA-II molecules are expressed on all B cells, on antigen presenting cells and on certain subsets of resting and activated T cells. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In pigs, this is referred to as the swine leukocyte antigen (SLA) region. There are 3 major MHC class II proteins encoded by the SLA which are SLA DP, SLA DQ and SLA DR. H6099-95Z immunoprecipitates a heterodimer composed of two polypeptides of 28 and 35kD from NP-40 extracts of biotin surface-labeled porcine peripheral blood mononuclear cells. This clone is reported to inhibit the mixed lymphocyte reaction and T cell stimulation induced by African swine fever virus and staphylococcal enterotoxin B.

Additional Text

Specificity

Recognizes porcine MHC class II DR molecules (SLA-II DR). Species Crossreactivity: bovine.

Purification

Protein A purified

Antibody Clonality

Monoclonal