ELAVL1 (Hu-antigen R, HuR, ELAV-like Protein 1, HUR) (MaxLight 650)

Catalogue Number: H7953-34E-ML650-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 4G8
Isotype: IgG1, kappa
Immunogen: ELAVL1 (AAH03376, 1-101aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Application: WB, IHC, FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. ELAVL1 is involved in 3'-UTR ARE-mediated MYC stabilization. It binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, HUR binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA and AUUUUUA motifs.

Additional Text

Accession Number

AAH03376

Specificity

Recognizes human ELAVL1.

Purification

Purified

Antibody Clonality

Monoclonal