Anti-Mouse IFNAR-1 [Clone MAR1-5A3] - DyLight® 650
Catalogue Number: I-1018-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 200 ug, 50 ug |
| Host name: | |
| Clone: | MAR1-5A3 |
| Isotype: | |
| Immunogen: | |
| Application: | FC |
Description
Description: IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β. Binding and activation of the receptor stimulates Janus protein kinases, which leads to the phosphorylation of several other proteins, namely STAT1 and STAT2. IFNAR1 has also been shown to interact with PRMT1 and Tyrosine kinase 2. Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.
Additional Text
Concentration
0.2 mg/ml
Antibody Clonality
Monoclonal
Storage Note
This DyLight® 650 conjugate is stable when stored at 2-8°C. Do not freeze.
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