Anti-Mouse IL-4 (Clone 11B11) - DyLight® 488

Catalogue Number: I-1077-LET

Manufacturer:Leinco Technologies, Inc
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name:
Clone: 11B11
Isotype:
Immunogen:
Application: FC, ICC

Description

Description: IL-4 antibody, 11B11, recognizes mouse IL-4, also known as B-cell differentiation factor (BCDF) and B-cell stimulatory factor (BSF1). IL-4 is a pleiotropic 20 kDa cytokine secreted by T helper 2 cells (Th2) cells, natural killer T (NKT) cells, mast cells, eosinophils, and basophils1,2. IL-4 signaling through the IL-4 receptor alpha chain (IL-4Ra) induces the differentiation of naive T cells to Th2 cells3,4 and stimulates B cell differentiation, proliferation, and class switching to IgG1 and IgE isotypes5. In addition, IL-4 is implicated in normal wound healing6,7 and airway inflammation in patients with asthma8.

Additional Text

Concentration

0.2 mg/ml

Antibody Clonality

Monoclonal

Storage Note

This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.