Anti-Mouse IL-2 [Clone JES6-1A12] - DyLight® 550
Catalogue Number: I-1088-LET
| Manufacturer: | Leinco Technologies, Inc |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 200 ug, 50 ug |
| Host name: | |
| Clone: | JES6-1A12 |
| Isotype: | |
| Immunogen: | |
| Application: | FC, ICC |
Description
Description: IL-2 is a 17.2 kD cytokine signaling protein that is the regulator of the proliferative and suppressive phases of the immune response, and stimulates growth and differentiation of B cells, NK cells, LAK cells, monocytes, and oligodendrocytes. It functions as a primary regulator of T cell homeostasis. Il-2 regulates the activities of white blood cells and plays a role in the immune system via "self" and "non-self" discrimination. IL-2 is a prime candidate in immunotherapeutics for both increasing T cell levels/function and for augmenting vaccine-elicited viral-specific T cell responses. IL-2 signal can be transduced via 3 different signaling pathways that include the JAK-STAT, PI3K/Akt/mTOR and MAPK/ERK pathways. Aldesleukin is a form of recombinant interleukin-2 for the treatment of cancers including malignant melanoma and renal cell cancer. Furthermore, there is additional therapeutic potential for IL-2 mAb use with transplants and autoimmune disease.
Additional Text
Concentration
0.2 mg/ml
Antibody Clonality
Monoclonal
Storage Note
This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.
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