Anti-Mouse IFN-γ

Catalogue Number: I-669-LET

Manufacturer:Leinco Technologies, Inc
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Unconjugated
Shipping Condition:RT
Unit(s): 500 ug
Host name:
Clone: 37895
Isotype:
Immunogen:
Application: FC, WB, NT, MC

Description

Description: Mouse IFN-gamma is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-gamma receptors are present in most immune cells, which respond to IFN-gamma signaling by increasing the surface expression of class I MHC proteins. This promotes the presentation of antigen to T-helper (CD4+) cells. IFN-gamma signaling in antigen-presenting cells and antigen-recognizing B and T lymphocytes regulates the antigen-specific phases of the immune response. Additionally, IFN-gamma stimulates a number of lymphoid cell functions including the anti-microbial and anti-tumor responses of macrophages, NK cells, and neutrophils. Human IFN-gamma species-specific and is biologically active only in human and primate cells.

Additional Text

Antibody Clonality

Monoclonal

Storage Note

The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.