Insulin Receptor R (Insulin Receptor-related Protein, Insulin Receptor-related Receptor, IR-related Receptor, INSRR, IRR) (MaxLight 650)
Catalogue Number: I7661-26S-ML650-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 6E6 |
| Isotype: | IgG1, kappa |
| Immunogen: | INSRR (NP_055030, 651-760aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD. |
| Application: | WB, IHC, FLISA |
Description
Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn't bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.
Additional Text
Accession Number
NP_055030
Specificity
Recognizes human INSRR.
Purification
Purified
Antibody Clonality
Monoclonal
I7661-26S-ML650 Datasheet
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