Integrin alphaV, beta3 (MaxLight 550)
Catalogue Number: I7661-37E-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | antigen identified by monoclonal antibody L230|CD51|integrin alpha-V|integrin alphaVbeta3|integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)|MSK8|vitronectin receptor subunit alpha|VNRA|VTNR |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2Q880 (LM609) |
| Isotype: | IgG1 |
| Immunogen: | Purified adhesion receptor from the human melanoma cell line M21. |
| Application: | FC, ICC, IF, IP, IHC |
Description
Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. The integrin family of cell adhesion receptors consists of a least 16 membrane-associated heterodimers, composed of an alpha and beta subunit that associate in a non-covalent manner. The structure and functional diversity of the integrin family are based on the pairing abilities of the alpha and beta subunits. The integrins are involved in vascular proliferation, adhesion and wound repair. AlphaVbeta3 appears to be selectively expressed on growing blood vessels and has been identified as a marker of angiogenic vascular tissue.
Additional Text
Gene Name
ITGAV
Gene ID
3685
Uniprot ID
P06756
Specificity
Recognizes the human vitronectin receptor aVb3 complex, an RGD-directed adhesion receptor. Species Crossreactivity: Avian, bovine, canine, chicken, monkey, porcine and rabbit. Not reactive with rat.
Purification
Protein A purified
Accession Number
NM_002210.2
Antibody Clonality
Monoclonal
I7661-37E-ML550 Datasheet
SUPPORT
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