Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla, ITGB1, Fibrinogen Receptor beta Subunit, FNRB, Integrin VLA4 Subunit beta, MDF2, MSK12, Very Late Activation Protein beta Polypeptide, VLAB, VLAbeta) (PE)
Catalogue Number: I7661-38R4-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile 40-50% glycerol, ddH2O. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Hamster |
| Clone: | HM beta 1-1 |
| Isotype: | IgG |
| Immunogen: | Purified mouse VLA-4 antigen. |
| Application: | FC |
Description
Description: The integrin beta 1 subunit (CD29) is a 110KD cell surface glycoprotein that is widely expressed by a variety of cells including all leukocytes. CD29 forms non-covalent bonds with the integrin alpha subunits, including CD51 and CD49a-f, to form heterodimers. The ligands for these heterodimers include collagen, fibronectin, laminin and vascular adhesion molecule-1. In the immune system beta 1 integrins play an important role in cell adhesion, migration, activation and differentiation.
Additional Text
Caution
FOR RESEARCH USE ONLY
Specificity
Recognizes the murine integrin beta 1 subunit. Inhibits beta 1 integrin mediated adhesion. Species Crossreactivity: rat.
Purification
Protein G purified
Antibody Clonality
Monoclonal
I7661-38R4 Datasheet
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