Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla) (MaxLight 490)

Catalogue Number: I7661-39J-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	4633401G24Rik\|AA409975\|AA960159\|CD29\|fibronectin receptor subunit beta\|Fnrb\|Gm9863\|gpIIa\|integrin beta-1\|VLA-4 subunit beta
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Rat
Clone:	2Q841 (MB1.2)
Isotype:	IgG2a, kappa
Immunogen:	Mouse Integrin, beta1. Species sequence homology: rat.
Application:	FC, IP, WB, IHC

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Integrin beta 1 is a 130kD transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression.

Additional Text

Uniprot ID

P09055

Gene Name

ITGB1

Specificity

Recognizes b1 subunit of mouse VLA (b1) integrins at ~88kD, and ~130kD with glycosylation. Species sequence homology: rat.

Gene ID

16412

Purification

Protein A purified

Antibody Clonality

Monoclonal

I7661-39J-ML490 Datasheet

Price

£1,070.00

-

Quantity
Unit Size

Find out about delivery