Integrin, beta1 (CD29, Very Late Antigen, VLAb1, Platelet gplla) (HRP)
Catalogue Number: I7661-39T-HRP-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with horseradish peroxidase (HRP). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2Q847 (P5D2) |
| Isotype: | IgG1 |
| Immunogen: | Human keratinocytes derived from skin. |
| Application: | ELISA, ICC, IP, RIA, IHC |
Description
Description: CD29 is the integrin B1 chain which is expressed as heterodimer non-covalently associated with the integrin subunits 1 to 6 (CD49a to CD49f) and known as very late antigens (VLA). It is also called platelet GPlla. It has been reported as receptor of fibronectin. The antigen mediates cellular adhesion primarily to collagen, laminin or fibronectin. It has a broad cellular reactivity but is not expressed by erythrocytes. In normal peripheral blood CD29 blood CD29 is found on approximately 41% of T cells, 40% of CD4+ T lymphocytes, 43% of CD8+ T lymphocytes (1). It is slightly reactive with peripheral B-cells. The co-expression of CD4 and CD29 allows the identification of the helper/inducer subpopulation of CD4 lymphocytes.
Additional Text
Gene ID
3688
Gene Name
ITGB1
Uniprot ID
P05556
Specificity
Recognizes human Integrin beta 1.
Purification
Protein A purified
Antibody Clonality
Monoclonal
I7661-39T-HRP Datasheet
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