Integrin, beta3 (ITGB3, CD61, GP3A, GPIIIa, HPA-1, NAIT, Platelet Fibrinogen Receptor beta Subunit, Platelet Glycoprotein IIIa, Platelet Membrane Glycoprotein IIIa) (FITC)

Catalogue Number: I7661-42A3F-USB

Manufacturer:United States Biological
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ug
Host name: Hamster
Clone: HM beta 3.1
Isotype: IgG
Immunogen: Mouse alpha 5 beta 3 protein purified from the mouse hybridoma 2B4.
Application: FC

Description

Description: Integrin beta 3 subunit (CD61) is a ~90kD a type I membrane protein, expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin.

Additional Text

Gene Name

ITGB3

Gene ID

16416

UniProt ID

O54890

Purification

Protein G purified

Antibody Clonality

Monoclonal