Interleukin 1 Receptor Type II (IL-1RII, IL-1R2, CD121b, CDw121B, IL-1R beta, IL1-Rb, MGC47725, p68) (Carboxyfluorescein)
Catalogue Number: I7663-25H3-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with Carboxyfluorescein (CFS). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Mouse |
| Clone: | 9L837 |
| Isotype: | IgG1 |
| Immunogen: | Purified, insect cell line Sf21-derived, recombinant human IL-1R II (aa14-343; Accession # P27930). |
| Application: | FC |
Description
Description: Interleukin-1 receptor II (IL-1 RII), also known as CD121b, is an immunoglobulin superfamily receptor that binds the pleiotropic cytokines, IL-1alpha and IL-1beta. It acts as an IL-1 antagonist because it has a short cytoplasmic domain and does not transduce IL-1 signals. IL-1 RII exists both as a transmembrane protein and as a soluble form that is released by proteolysis.
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene ID
7850
Gene Name
IL1R2
Uniprot ID
P27930
Specificity
Recognizes human IL-1 RII.
Purification
Protein A purified
Antibody Clonality
Monoclonal
I7663-25H3 Datasheet
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