Interleukin 6 (IL-6, B cell Stimulatory Factor 2, BSF2, Cytotoxic T cell Differentiation Factor, CTL Differentiation Factor, CDF, Hepatocyte Stimulating Factor, HSF, Hybridoma Growth Factor, HGF, Hybridoma Plasmacytoma Growth Factor, HPGF, Interferon beta

Catalogue Number: I8428-06B-ML490-USB

Manufacturer:United States Biological
Preservative:Azide-free
Type:Monoclonal Primary Antibody - Conjugated
Alias:B-cell hybridoma growth factor|Il-6|interleukin HP-1|interleukin-6
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rat
Clone: 6D495 (6B4 IGH 54)
Isotype: IgG1
Immunogen: Recombinant protein corresponding to mouse IL-6 (interleukin-6)
Application: FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Mouse IL-6 (interleukin-6) is a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue.

Additional Text

Gene Name

IL6

Gene ID

16193

Uniprot ID

P08505

Antibody Clonality

Monoclonal

Full Name

Interleukin 6 (IL-6, B cell Stimulatory Factor 2, BSF2, Cytotoxic T cell Differentiation Factor, CTL Differentiation Factor, CDF, Hepatocyte Stimulating Factor, HSF, Hybridoma Growth Factor, HGF, Hybridoma Plasmacytoma Growth Factor, HPGF, Interferon beta 2, IFNB2) (Azide Free) (MaxLight 490)