Catalogue Number: I8428-06B-ML490-USB
| Manufacturer: | United States Biological |
| Preservative: | Azide-free |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | B-cell hybridoma growth factor|Il-6|interleukin HP-1|interleukin-6 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 6D495 (6B4 IGH 54) |
| Isotype: | IgG1 |
| Immunogen: | Recombinant protein corresponding to mouse IL-6 (interleukin-6) |
| Application: | FLISA |
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Mouse IL-6 (interleukin-6) is a multifunctional pro-inflammatory cytokine secreted by activated T cells, macrophages, endothelial cells, fibroblasts and osteoblasts, which acts as the principle inducer of the acute phase response in the liver. IL-6 signals through a membrane bound receptor complex consisting of the ligand-binding IL-6Ra chain (CD126) and the signal-transducing component gp130 (CD130), but can also stimulate cells expressing gp130 through a soluble IL-6R. IL-6 has been shown to stimulate B cell differentiation and subsequent immunoglobulin production, promote hybridoma growth, as well as regulating bone metabolism and stimulating energy mobilisation in muscle and fatty tissue.
IL6
16193
P08505
Monoclonal
Interleukin 6 (IL-6, B cell Stimulatory Factor 2, BSF2, Cytotoxic T cell Differentiation Factor, CTL Differentiation Factor, CDF, Hepatocyte Stimulating Factor, HSF, Hybridoma Growth Factor, HGF, Hybridoma Plasmacytoma Growth Factor, HPGF, Interferon beta 2, IFNB2) (Azide Free) (MaxLight 490)