IL12A (Interleukin-12 Subunit alpha, IL-12A, Cytotoxic Lymphocyte Maturation Factor 35kD Subunit, CLMF p35, IL-12 Subunit p35, NK Cell Stimulatory Factor Chain 1, NKSF1) (Carboxyfluorescein)

Catalogue Number: I8434-29E-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in sodium chloride, 0.5% BSA, 0.09% sodium azide. Labeled with Carboxyfluorescein.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 Tests
Host name:	Mouse
Clone:	11C30
Isotype:	IgG1
Immunogen:	Sf 21-derived, recombinant human IL-12 p35 subunit (rhIL-12 p35; Arg23-Ser219; Accession # P29459).
Application:	FC

Overview
Datasheets

Description

Description: Interleukin 12 (IL-12) and interleukin 35 (IL-35) are heterodimeric cytokines composed of alpha and beta chains. IL-12 is composed of p35 and p40 subunits, while IL-35 is comprised of p35 paired with EBI-3. In mice, IL-35 is produced by FoxP3+ regulatory T cells and may function as an inhibitory cytokine to suppress T cell proliferation. Human FoxP3+ Tregs do not constitutively express IL-35, but expression may be induced by activated dendritic cells.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene ID

3592

Gene Name

IL12A

Uniprot ID

P29459

Specificity

Recognizes human IL-12 p35.

Purification

Affinity Purified

Antibody Clonality

Monoclonal

I8434-29E Datasheet

Price

£664.00

-

Quantity
Unit Size

Find out about delivery