Interleukin 13 (IL-13) (FITC)
Catalogue Number: I8435-05-FITC-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with Fluorescein isothiocyanate (FITC). |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Rat |
| Clone: | 1.B2.1 |
| Isotype: | IgG1 |
| Immunogen: | Purified recombinant human IL-13 |
| Application: | FC, WB, IHC, FLISA, NT |
Description
Description: IL-13 is an immunoregulatory cytokine produced mainly by T helper 2 cells, but also by mast cells and NK cells. IL-13 is a unique cytokine having structural features and functional characteristics with IL-4. However, it only shares about 30% homology with the IL-4 sequence. IL-13 inhibits IL-1 beta, IL-6, IL-8, and TNF-alpha resulting in anti-inflammatory effects on monocytes and macrophages. It also induces B cells to proliferate and isotype-switch to the production of IgE. In addition, IL-13 modulates TH2 cell development interfering key roles in the ostracizing of gastrointestinal parasites and in the evolvement of asthma and allergy.
Additional Text
Purification
Protein A/G Purified
Specificity
Recognizes natural and recombinant human IL-13.
Antibody Clonality
Monoclonal
I8435-05-FITC Datasheet
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