Internexin, alpha (MaxLight 550)
Catalogue Number: I8442-74A-ML550-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservatives added. Labeled with MaxLight™550. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 3G169 |
| Isotype: | IgG1 |
| Immunogen: | Full-length recombinant rat alpha-internexin protein. |
| Application: | ICC, IF, WB, IHC, FLISA |
Description
Description: Alpha-internexin is a, 66kD, type IV intermediate filament protein(1) that is expressed in neurons during development of the peripheral and central nervous systems, as well as in a few neurons of the adult central nervous system. Recent studies have demonstrated that during neuronal development, alpha-internexin replaces type VI nestin and type III vimentin intermediate filament proteins. Clinical studies have also demonstrated that alpha-internexin may play a role in the development of neuronal polarity.
Additional Text
Specificity
Recognizes rat alpha-internexin at ~66kD. Species Crossreactivity: human, mouse and rabbit. Stains human neuron and nerve fiber in human cerebral cortex. Also stained glioma, ganglioneuroma, pheochromocytoma and paraganglioma in human tissue.
Purification
Protein A purified
Antibody Clonality
Monoclonal
I8442-74A-ML550 Datasheet
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