IL22RA1 (Interleukin-22 Receptor Subunit alpha-1, IL-22 Receptor Subunit alpha-1, IL-22R-alpha-1, IL-22RA1, Cytokine Receptor Class-II Member 9, Cytokine Receptor Family 2 Member 9, CRF2-9, ZcytoR11, IL22R) (PerCP)
Catalogue Number: I8443-10F-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in saline, 0.5% BSA, 0.09% sodium azide. Labeled with PerCP. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Rat |
| Clone: | 12K118 |
| Isotype: | IgG2a |
| Immunogen: | Recombinant protein corresponding to Thr18-Ala228 from mouse IL22RA1 expressed in NS0 cell line. Species Sequence Homology: human; 78%, rat; 94% |
| Application: | FC |
Description
Description: The interleukin-22 receptor A1 (IL-22 Ra1), also known as CRF2-9, is a 557aa, ~65kD type I transmembrane protein of the type II cytokine receptor family (CRF). IL-22 RA1 forms an IL-22 signaling complex with IL-10 RB/CRF2-4 on epithelial and stromal cells. IL-22 engagement of the signaling complex stimulates antimicrobial, acute phase and proinflammatory protein expression. IL-22 Ra1 also pairs with IL-20 RB to form a receptor that is responsive to IL-20 and IL-24. Within the 211aa extracellular domain, mouse IL-22 Ra1 shares 78% and 94% aa sequence identity with human and rat IL-22 RA1, respectively.
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene Name
IL22RA1
Specificity
Recognizes mouse IL22RA1.
Purification
Protein G purified
Gene ID
230828
Uniprot ID
Q80XZ4
Antibody Clonality
Monoclonal
I8443-10F Datasheet
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