Interleukin 22 (IL-22, IL-10 Related T cell-derived Inducible Factor, IL-TIF)

Catalogue Number: I8443-18T-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a powder lyophilized from a solution containing PBS with trehalose. Reconstitute with 1ml sterile PBS.
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	cytokine Zcyto18\|IL-10-related T-cell-derived inducible factor\|IL-21\|IL-22\|IL-D110\|ILTIF\|IL-TIF\|interleukin-22\|TIFa\|TIFIL-23\|zcyto18
Shipping Condition:	Blue Ice
Unit(s):	100 ug
Host name:	Mouse
Clone:	11D67
Isotype:	IgG1
Immunogen:	Recombinant human IL-22 (Ala34--Ile179) expressed in E. coli (Accession #Q9GZX6)
Application:	ELISA, NT

Overview
Datasheets

Description

Description: Interleukin 22 (IL-22), also called IL-10-related T cell-derived inducible factor or IL-TIF, is a secreted cytokine that contributes to the inflammatory response in vivo. IL-22 is expressed in T cells and mast cells in response to IL-9 or lipopolysaccharide. IL-22 monomers bind to a class II cytokine receptor that is a heterodimer of CRF2-9 (IL-22 Ra1) and CRF2-4 (IL-10 Rb). Human IL-22 is a 179aa protein with a 33aa signal peptide, three N-glycosylation sites and two intramolecular disulfide bonds; the mature protein shows 81% and 77% aa identity with mouse and rat IL-22, respectively.

Additional Text

Caution

FOR RESEARCH USE ONLY

Uniprot ID

Q9GZX6

Gene ID

50616

Gene Name

IL22

Specificity

Recognizes human IL-22. In direct ELISAs, this antibody shows 100% crossreactivity with recombinant mouse IL22 and recombinant rat IL22 and no crossreactivity with recombinant human IL10.

Purification

Protein G purified

Antibody Clonality

Monoclonal

I8443-18T Datasheet

Price

£832.00

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