Bulk Anti-Human CD16 (3G8) Antibody

Catalogue Number: ICH1010-ICB

Manufacturer:IchorBio
Type:Monoclonal Primary Antibody - Unconjugated
Alias:FCGR3A, Fc-gamma RIII, FcRIII
Shipping Condition:Blue Ice
Storage Condition:2-8°C
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Mouse
Clone: 3G8
Isotype: IgG1, kappa
Immunogen: Human PMN cells
Application: FC, IP, IHC-Fr, Blk, MC

Description

Description: CD16 is known as low affinity IgG receptor III (Fc gamma RIII) and is expressed as two distinct forms (CD16a and CD16b). CD16a (Fc gamma RIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (Fc gamma RIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils.

Additional Text

Gene ID

2214

Gene Name

FCGR3A

Uniprot ID

P08637

Caution

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality

Monoclonal

Concentration

≥ 2 mg/ml

Application Notes

Flow Cytometry: For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. Blocking: Clone 3G8 antibody blocks neutrophil phagocytosis and stimulates NK cell proliferation. Each investigator should determine their own optimal working dilution for specific applications.

Storage Note

anti-CD16 In Vivo Antibody - Low Endotoxin (3G8) is stable when stored at 2-8°C.

Purification

This monoclonal antibody was purified using Protein A

Price
£2,265.00


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