Anti-CD80 (16-10A1) In Vivo Antibody - Low Endotoxin
Catalogue Number: ICH1037-ICB
| Manufacturer: | IchorBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Activation B7-1 antigen, B7 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Armenian Hamster |
| Clone: | 16-10A1 |
| Isotype: | IgG |
| Immunogen: | Purified Recombinant Mouse CD80 (>98%) |
| Application: | FC, IP, WB, IHC-Fr, Blk |
Description
Description: CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
Additional Text
Gene Name
CD80
Gene ID
12519
Concentration
0.5 mg/ml
Uniprot ID
Q00609
Caution
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Antibody Clonality
Monoclonal
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Storage Note
anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Purification
This monoclonal antibody was purified using Protein A
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
ICH1037 Datasheet
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