Anti-Mouse CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98)

Catalogue Number: ICH1068UL-ICB

Manufacturer:IchorBio
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor (EC:2.7.10.1), CSF-1-R, CSF-1R, M-CSF-R, Proto-oncogene c-Fms, Csf1r, Csfmr, Fms
Shipping Condition:Blue Ice
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Rat
Clone: AFS98
Isotype: IgG2a, kappa
Immunogen: Purified Recombinant Mouse M-CSFR
Application: FC, WB, FA, Blk

Description

Description: Macrophage colony-stimulating factor (M-CSF, also termed CSF-1) receptor is an integral membrane tyrosine kinase, expressed in monocytes (macrophages and their progenitors) and drives growth and development of this blood cell lineage. It also triggers growth and development of mononuclear phagocytes and placental trophoblasts. M-CSF receptor is present in osteoclasts both at mRNA and protein levels. When M-CSF ligand specifically binds to the M-CSF receptor on osteoclasts, it induces receptor dimerization, activation and autophosphorylation of cytoplasmic tyrosine residues M-CSF and its receptor present as candidate therapeutic targets in states of inflammatory bone erosion.

Additional Text

Gene Name

CSF1R

Uniprot ID

P09581

Purification

Protein A/G Purified

Gene ID

12978

Caution

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Concentration

1-5 mg/ml

Antibody Clonality

Monoclonal

Application Notes

Each investigator should determine their own optimal working dilution for specific applications.

Storage Note

anti-CD115 In Vivo Antibody - Ultra Low Endotoxin (AFS98) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. and keep sterile.

Price
£3,125.00


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