Anti-Mouse CD120a In Vivo Antibody - Low Endotoxin (55R-593) [ICH1069]

Catalogue Number: ICH1069-ICB

Manufacturer:	IchorBio
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	Tumor necrosis factor receptor superfamily member 1A, Tnfrsf1a, TNF-R1, TNF-RI, p55, p60
Shipping Condition:	Blue Ice
Unit(s):	100 mg, 25 mg, 5 mg, 50 mg
Host name:	Armenian Hamster
Clone:	55R-593
Isotype:	IgG1
Immunogen:	E. coli-expressed extracellular domain of the mouse TNFRI protein
Application:	IP, WB

Overview
Datasheets

Description

Description: Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-A and TNF-B (also known as LT-A). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-κB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

Additional Text

Gene Name

TNFRSF1A

Uniprot ID

P25118

Concentration

1 mg/ml

Purification

Protein A/G Purified

Gene ID

21937

Caution

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality

Monoclonal

Application Notes

Each investigator should determine their own optimal working dilution for specific applications.

Storage Note

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C.

ICH1069 Datasheet

Price

£2,539.00

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