Anti-Mouse IL-1b In Vivo Antibody - Low Endotoxin (B122)

Catalogue Number: ICH1100-ICB

Type:Monoclonal Primary Antibody - Unconjugated
Alias:Interleukin-1 beta, IL-1B
Shipping Condition:Blue Ice
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Armenian Hamster
Clone: B122
Isotype: IgG
Immunogen: E. coli -expressed, recombinant mouse IL-1β
Application: ELISA, IP, WB, NT


Description: Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes. IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease. The B122 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-1β.

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Uniprot ID


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1 mg/ml

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Protein A/G Purified


Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality


Application Notes

Each investigator should determine their own optimal working dilution for specific applications.

Storage Note

anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.


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