Anti-Mouse RANKL In Vivo Antibody - Low Endotoxin (IK22/5)

Catalogue Number: ICH1114-ICB

Type:Monoclonal Primary Antibody - Unconjugated
Alias:Tumor necrosis factor ligand superfamily member 11, Tnfsf11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE, CD254
Shipping Condition:Blue Ice
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Rat
Clone: IK22/5
Isotype: IgG2a, kappa
Immunogen: Purified Recombinant Mouse RANKL (NSO-derived)
Application: FC, IF, IP, WB, IHC-Fr, Blk


Description: RANKL (Receptor Activator for Nuclear Factor κ B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor), is a member of the tumor necrosis factor family cytokine. RANKL is essential for osteoclast formation, activation, and survival. RANKL through interaction with its receptor RANK can modulate matrix degradation and inflammation. RANKL and RANK have essential roles in lymph node formation, establishment of the thymic microenvironment, and development of a lactating mammary gland during pregnancy. Consequently, novel drugs specifically targeting RANK, RANKL, and their signaling pathways in osteoclasts are expected to revolutionize the treatment of various ailments associated with bone loss, such as arthritis, periodontal disease, cancer metastases, and osteoporosis.

Additional Text

Uniprot ID



1 mg/ml

Gene Name



Protein A/G Purified

Gene ID



Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality


Application Notes

Each investigator should determine their own optimal working dilution for specific applications.

Storage Note

anti-RANKL In Vivo Antibody - Low Endotoxin (IK22/5) is stable when stored at 2-8°C. Do not freeze.This antibody is


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