Anti-Mouse, Human CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2)
Catalogue Number: ICH1130-ICB
| Manufacturer: | IchorBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Leukocyte common antigen, L-CA, T200, CD45, Receptor-type tyrosine-protein phosphatase C, PTPRC, B220 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Rat |
| Clone: | RA3-6B2 |
| Isotype: | IgG2a |
| Immunogen: | Abelson murine leukemia virus-induced pre-B tumor cells |
| Application: | ELISA, FC, IF, IHC-P, IP, WB, IHC-Fr, FA |
Description
Description: CD45R, also known as B220 is a 220 kDa transmembrane protein tyrosine phosphatase expressed on B cells and some subsets of T and NK cells. This antibody is commonly used as a B cell marker as CD45R does play a critical role in TCR and BCR signaling.
Additional Text
Gene Name
PTPRC
Gene ID
5788
Uniprot ID
P08575
Concentration
0.5 mg/ml
Caution
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Antibody Clonality
Monoclonal
Application Notes
Functional Assay: In vivo treatment with Rat Anti-Mouse CD45R (Clone RA3-6B2) reduces the number of T and B cells and modifies their functional activity. Each investigator should determine their own optimal working dilution for specific applications.
Storage Note
Anti-CD45R In Vivo Antibody - Low Endotoxin (RA3-6B2) is stable for at least four (4) weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
ICH1130 Datasheet
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