Anti-Mouse PD-1 In Vivo Antibody - Ultra Low Endotoxin (RMP1-14)

Catalogue Number: ICH1132UL-ICB

Type:Monoclonal Primary Antibody - Unconjugated
Alias:Programmed cell death protein 1, Pdcd1, CD279
Shipping Condition:Blue Ice
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Rat
Clone: RMP1-14
Isotype: IgG2a, kappa
Immunogen: Mouse PD-1 transfected BHK cells
Application: FC, WB, FA, Blk


Description: CD279, also known as programmed death-1 (PD-1) is a 50-55 kD immunoglobulin superfamily member. PD-1 is expressed on a subset of CD4-CD8- thymocytes, and on activated T and B cells. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. This RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production.

Additional Text

Gene Name



Protein A/G Purified

Gene ID


Uniprot ID



Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality


Application Notes

Blocking: Clone RMP1-14 antibody has been shown to block the binding of both mouse PD-L1-Ig and mouse PD-L2-Ig to PD-1. For immune checkpoint antibodies 200 ug per mouse per injection is the standard dosage in the literature. For this anti-PD-1 (clone RMP1-14), we suggest to inject 200 ug/mouse ip generally on days 3, 6 and 9, post injection of tumor. Sometime up to six injections depending on the length of the experiment may be required. Each investigator should determine their own optimal working dilution for specific applications.


≥ 2 mg/ml

Storage Note

anti-PD-1 In Vivo Antibody - Ultra Low Endotoxin (RMP1-14) is stable when stored at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.


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