Anti-Mouse TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 )

Catalogue Number: ICH1136UL-ICB

Type:Monoclonal Primary Antibody - Unconjugated
Alias:Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2
Shipping Condition:Blue Ice
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Armenian Hamster
Clone: TN3-19.12
Isotype: IgG
Immunogen: Recombinant mouse TNFalpha
Application: FC, IP, WB, FA, Blk


Description: The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha

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Protein A/G Purified


Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality


Application Notes

Each investigator should determine their own optimal working dilution for specific applications.


≥ 2 mg/ml

Storage Note

anti-TNF alpha In Vivo Antibody - Ultra Low Endotoxin (TN3-19.12 ) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.


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