Anti-Mouse TCR Beta (H57-597) Antibody In Vivo Antibody - Low Endotoxin

Catalogue Number: ICH1153-ICB

Manufacturer:	IchorBio
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	TCR-β chain, TCR-β, β-TCR
Shipping Condition:	Blue Ice
Unit(s):	100 mg, 25 mg, 5 mg, 50 mg
Host name:	Armenian Hamster
Clone:	H57-597
Isotype:	IgG
Immunogen:	Affinity purified TCR from mouse DO-11.10 cells
Application:	FC, IHC-P, IP, IHC-Fr, Depl, Stim

Overview
Datasheets

Description

Description: TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.

Additional Text

Caution

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality

Monoclonal

Application Notes

The suggested concentration for this TCR β chain (clone H57-597) antibody for staining cells in flow cytometry is ≤ 0.25 µg per 10^6 cells in a volume of 100 µl. Titration of the reagent is recommended for optimal performance for each application.

Concentration

≥ 5 mg/ml

Storage Note

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Purification

This monoclonal antibody was purified using Protein A

ICH1153 Datasheet

Price

£2,265.00

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