Anti-Mouse TCR beta In Vivo Antibody - Low Endotoxin (H57-597) [ICH1153]

Catalogue Number: ICH1153-ICB

Manufacturer:	IchorBio
Type:	Monoclonal Primary Antibody - Unconjugated
Alias:	TCR-β chain, TCR-β, β-TCR
Shipping Condition:	Blue Ice
Unit(s):	100 mg, 25 mg, 5 mg, 50 mg
Host name:	Armenian Hamster
Clone:	H57-597
Isotype:	IgG
Immunogen:	Affinity purified TCR from mouse DO-11.10 cells
Application:	FC, IHC-P, IP, IHC-Fr, Depl, Stim

Overview
Datasheets

Description

Description: TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.

Additional Text

Purification

Protein A/G Purified

Caution

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Antibody Clonality

Monoclonal

Application Notes

The suggested concentration for this TCR β chain (clone H57-597) antibody for staining cells in flow cytometry is ≤ 0.25 µg per 10^6 cells in a volume of 100 µl. Titration of the reagent is recommended for optimal performance for each application.

Concentration

≥ 5 mg/ml

Storage Note

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

ICH1153 Datasheet

Price

£2,539.00

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