Anti-Mouse CD105 In Vivo Antibody (MJ7/18) - Low Endotoxin [ICH1191]

Catalogue Number: ICH1191-ICB

Manufacturer:IchorBio
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Endoglin, Ancillary TGF-beta Receptor
Shipping Condition:Blue Ice
Unit(s): 100 mg, 25 mg, 5 mg, 50 mg
Host name: Rat
Clone: MJ7/18
Isotype: IgG2a, kappa
Immunogen: MJ7/18 was produced by immunizing rats with inflamed mouse skin and selecting for reactivity with endothelial cells. MJ7/18 predominantly stains vascular endothelial cells and is a marker of mouse endothelium
Application: ELISA, FC, IF, IHC-P, IP, WB, IHC, Agon, Separation, LCImg

Description

Description: CD105 (endoglin) is a TGF-β superfamily co-receptor that promotes angiogenesis, is involved in endothelial integrin-mediated mural cell and leukocyte adhesion, antagonizes TGF-β mediated ERK activation, is essential to the immune response of macrophages, regulates trophoblast differentiation and invasion during pregnancy, promotes T-cell proliferation, and regulates differentiation and collagen expression in myofibroblasts

Additional Text

Purification

Protein A/G Purified

Antibody Clonality

Monoclonal

Application Notes

Each investigator should determine their own optimal working dilution for specific applications.

Concentration

≥ 2 mg/ml

Price
£2,539.00


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