Anti-Mouse CD24 In Vivo Antibody (M1/69) - Low Endotoxin [ICH1192]
Catalogue Number: ICH1192-ICB
| Manufacturer: | IchorBio |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | Heat Stable Antigen, Nectadrin, Ly-52 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 mg, 25 mg, 5 mg, 50 mg |
| Host name: | Rat |
| Clone: | M1/69 |
| Isotype: | IgG2b, kappa |
| Immunogen: | M1/69 was generated by fusing the spleen cells of a DA rat immunized with B10 mouse spleen cells enriched for T cells with cells from a nonsecreting mouse myeloma line (NSI) |
| Application: | FC, IF, IP, WB, IHC, inELISA, Inh |
Description
Description: Mouse CD24 is a small 27 amino acid sialoglycoprotein that is anchored to plasma membranes via a glycosyl-phosphatidylinositol linker. CD24 is widely distributed and plays a role in many diverse functions including adaptive immunity, inflammation, autoimmunity, and cancer. CD24 modulates growth and differentiation signals to granulocytes and B cells, is required for homeostatic cell renewal, binds to P-selectin on activated endothelial cells, plays a role in cell adhesion, lymphocyte proliferation for homeostatic purposes4, lymphocyte costimulation via CD28-independent pathways as well as a crucial role in cell selection and maturation during hematopoiesis.
Additional Text
Purification
Protein A/G Purified
Antibody Clonality
Monoclonal
Application Notes
Each investigator should determine their own optimal working dilution for specific applications.
Concentration
≥ 2 mg/ml
SUPPORT
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PRODUCT
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DELIVERY
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